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msd pstat3 assay  (Meso Scale Diagnostics LLC)

 
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    Meso Scale Diagnostics LLC msd pstat3 assay
    Msd Pstat3 Assay, supplied by Meso Scale Diagnostics LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/msd pstat3 assay/product/Meso Scale Diagnostics LLC
    Average 90 stars, based on 1 article reviews
    msd pstat3 assay - by Bioz Stars, 2026-02
    90/100 stars

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    PI3Kγδ inhibitor, AZD8154, suppresses antigen induced increases in lung tissue pAkt levels, a downstream marker of PI3K activation. The impact of AZD8154 and budesonide on PI3K ( A & B ), JAK/STAT ( C & D ) and NF-κB ( E ) pathways was assessed in the lung tissue 2 hours after antigen (OVA) challenge. Data are presented as boxes (Q2 to Q3 with the median) and whiskers (min to max). Statistically significant differences between Saline/Vehicle and other groups as presented as ** p < 0.01; statistically significant differences between OVA/Vehicle and other groups are presented as ## p < 0.01, ### p < 0.001 and #### p < 0.0001. One experiment ( n = 5–6)

    Journal: Respiratory Research

    Article Title: PI3Kγδ inhibition suppresses key disease features in a rat model of asthma

    doi: 10.1186/s12931-024-02814-1

    Figure Lengend Snippet: PI3Kγδ inhibitor, AZD8154, suppresses antigen induced increases in lung tissue pAkt levels, a downstream marker of PI3K activation. The impact of AZD8154 and budesonide on PI3K ( A & B ), JAK/STAT ( C & D ) and NF-κB ( E ) pathways was assessed in the lung tissue 2 hours after antigen (OVA) challenge. Data are presented as boxes (Q2 to Q3 with the median) and whiskers (min to max). Statistically significant differences between Saline/Vehicle and other groups as presented as ** p < 0.01; statistically significant differences between OVA/Vehicle and other groups are presented as ## p < 0.01, ### p < 0.001 and #### p < 0.0001. One experiment ( n = 5–6)

    Article Snippet: 10 μg of protein from lung tissue extract were utilized in pAkt (T308); pSTAT3, pSTAT4 & STAT5a, b (Phospho-STAT Panel kit) MSD Assay plates (Meso Scale Delivery, USA) and run according to manufacturers’ instructions.

    Techniques: Marker, Activation Assay, Saline